Journal No.: 1400.05.02
Karl Fischer reagents are used in the Karl Fischer titration process. Karl Fischer titration is a method to determine the water content in the sample, whose reagent consists of iodine, sulfur dioxide, an organic base (pyridine or imidazole) and an alcohol (such as methanol, ethanol, propanol or diethylene glycol). Ethyl ether) is formed.
In the past, in the production of Karl Fischer solutions, only pyridine was used as a base, which is a toxic and smelly substance. Therefore, in order to correct this problem, trying to replace pyridine with an organic base with a similar function and less toxicity led to the selection It was again imidazole. Karl Fischer reagents made on the basis of imidazole have more stability and less toxicity than pyridine-based samples, so consumers are more receptive to these solutions.
Dr. Majalli Chemical Industries Complex currently produces two types of Karl Fischer solutions, one with pyridine and the other without pyridine, and provides them in dark colored glass bottles. The most important features of Dr. Majalli Chemical Industries Karl Fischer products:
Long shelf life
Achieving highly repeatable results
No sedimentation and clogging in titrator devices
The ability to quickly send the product to the customer in a very short time after production
The possibility of production and delivery with invoices of 1, 3, 5 or any other customized invoice
Can be used for all samples (including alcohols, ketones, aldehydes, etc.)
| Technical specifications of Karl Fischer solution | Karl Fischer solution |
| Single Component Reagent with pyridine 1mL≈ 5mg H2O | Karl Fischer Reagent 5 (1L) |
| Single Component Reagent free pyridine 1mL ≈ 5 mg H2O | Karl Fischer Reagent 5 (1L) |
| Single Component Reagent with pyridine 1mL≈ 3mg H2O | Karl Fischer Reagent 3 (1L) |
| Single Component Reagent free pyridine 1mL ≈ 3 mg H2O | Karl Fischer Reagent 3 (1L) |
tip
The general Karl Fischer reaction in methanol solution is as follows
CH3OH + SO2 + RN → [RNH]+ + –SO3 CH3
H2O + I2 + [RNH] + –SO3 CH3 +2 RN → [RNH] SO4 CH3 + 2[RNH] I
Sulfur dioxide forms an ether with methanol, which is neutralized by a base. In Karl Fischer titration, alkyl sulfite anion is oxidized by iodine to alkyl sulfate. This reaction leads to water consumption.
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